Although a nuisance, cold sores are not a health hazard for the majority of patients. However, patients who are immunocompromised pose a special risk for serious and possible fatal consequences from the primary infection or RHL.

These include patients who...

• Suffer from atopic dermatitis. The herpetic virus can affect this condition, causing eczema herpeticum. If this happens, the HSV-1 may be disseminated to the visceral organs, possibly leading to death
• Are in an immunocompromised state from cancer, drug therapy or HIV
• Have had their immune systems suppressed during cancer treatments or transplant procedures

Pharmacists should appropriately assess the patient's needs based on the severity of the symptoms being presented, the underlying condition and previous attempts at treatment.

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