Prevalence of HSV-1 infection is estimated to be between 50 and 98% of the US adult population. Seroprevalence of HSV-1 reaches >40% by age 15 and increases to 60 to 90% in older adults.1-4 However, many who have the virus never get cold sores. In fact, only about 20% of those infected will experience outbreaks. The average number of outbreaks is 1 to 3 per year. The reason some infected individuals get cold sores and some don't is still unknown.1-4

1. Raborn GW Pharmacodynamic Considerations in the Treatment of Cold Sores: A comparative Look at Available Treatments. PowerPac CE,Dec 2006
2. Smith JS, Robinson NJ. Age specific prevalence of infection with herpes simplex virus types 2 and 1: a global review. J Infect Dis. 2002;186(suppl 1):S3-S28.
3. Schulman J. Recurrent herpes labialis in US children and youth. Community Dent Oral Epidemiol. 2004;32:402-409.
4. Looker KJ, Garnett GP. A systematic review of the epidemiology and interaction of herpes simplex virus types 1 and 2. Sex Transm Infect. 2005;81:103-107Smith

*ABREVA Risk-Free Guarantee: If you aren't completely satisfied for any reason, save your receipt and remaining product, and call 1-877-709-3539 to get your money back.