Even when a cold sore is healed, the virus lies dormant in the ganglia of the trigeminal nerve waiting to strike again. When triggered, the virus travels back through the sensory nerve pathways (where it has been lying dormant) and an outbreak occurs.
These outbreaks can often appear in the same vicinity as the initial infection.
1. Raborn GW Pharmacodynamic Considerations in the Treatment of Cold Sores: A comparative Look at Available Treatments. PowerPac CE, Dec 2006
2. Pelegrin GM. Treating the cold sore, not just the symptoms. Pharmacy Times: Pharmacist Edition: September, 2007
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